Endoglin antibody

Catalog No. ABIN7670168

This anti-Endoglin antibody is a Mouse Monoclonal antibody detecting Endoglin in FACS. Suitable for Human.

Quick Overview for Endoglin antibody (ABIN7670168)

Target: Endoglin (ENG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: SN6

Product Details anti-Endoglin Antibody

Purpose: AF/LE Purified Anti-Human CD105 Antibody[SN6]

Endotoxin Level: Low Endotoxin

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Preservative: Azide free

Handling Advice: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiry Date: 12 months

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background: HHT,RP11 228B,Osler Rendu Weber syndrome,END,HHT1,ORW1,CD105,ENG,endoglin,AI528660,AI662476,CD 105,CD105 antigen,EGLN,FLJ41744,ORW,Osler Rendu Weber syndrome 1,RP11 228B15.2,S-endoglin,SN6,AI528660,AI662476,CD 105,CD105,CD105 antigen,EGLN,END,Endoglin,Eng,FLJ41744,HHT1,ORW,ORW1,Osler Rendu Weber syndrome 1,RP11 228B15.2,S-endoglin,SN6,ENG,END,Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3). Endoglin and Betaglycan/T beta RIII are type III receptors for TGF beta superfamily ligands, sharing 71 % aa identity in the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta, with lower amounts on hematopoietic, mesenchymal and neural crest stem cells, activated monocytes, and lymphoid and myeloid leukemic cells.

UniProt: P17813